Arjun Reddy, a medico with anger management issues, gets into a brawl with another student and is asked to either apologize or leave college. Arjun prepares to leave but stays back after seeing a first year student, Preethi Shetty. Arjun, along with his friend Shiva, goes to first year class room and announces that he is in love with Preethi and she is exclusive to him. Preethi, although initially afraid of his nature, eventually reciprocates his feelings and their relationship grows stronger over the course of next 3 years. Preethi’s father rejects him on the grounds of caste and arranges her marriage with someone else. Arjun protests in front of her house and gets arrested. His father ostracizes him from home for damaging family reputation. He gets an apartment flat with the help of his friend Shiva and joins as a house surgeon in a leading hospital. Unable to forget her, he becomes alcoholic and drug addict. He befriends one of his patients and a leading film star, Jia Sharma, and …